新生儿血清胆红素与肌酸激酶同工酶的关系  

Relationship between Bilirubin and Serum CK-MB

作　　者：祝伟[1] 王广州[1] 郭晓燕[1] 

机构地区：[1]河南省漯河市中心医院儿科,河南省漯河市462000

出　　处：《中国全科医学》2008年第14期1293-1294,共2页Chinese General Practice

摘　　要：目的观察新生儿血清胆红素与肌酸激酶同工酶(CK-MB)的关系,探讨新生儿血清胆红素与心肌损害的关系。方法对40例正常新生儿、40例生理性黄疸新生儿、40例病理性黄疸新生儿的CK-MB水平进行测定并比较。结果正常组新生儿的CK-MB水平与生理性黄疸组、病理性黄疸组的比较差异均有统计学意义(P<0.01),生理性黄疸组与病理性黄疸组间差异亦有统计学意义(P<0.01)。结论高胆红素可引起心肌损害,血清CK-MB可作为胆红素对心肌细胞损伤的一个重要生化指标。Objective To measure the changes of serum CK - MBs concentration in neonates suffering from pathologic jaundice. Methods Forty neonates with pathologic jaundice, 40 with physiologic jaundice and 40 normal were enrolled to detect bilirubin and serum CK - MB concentration. Results There was significant difference in serum CK - MBs concentration between 3 groups （ P 〈0. 01 ）. The CK- MB concentration of pathologic jaundice group was significantly higher than that of the other two （ P 〈 0. 01 ）. Conclusion High bilirubin can cause myocardial damage. Serum CK - MB can be used as a key biochemical indicators of myocardial injury due to bilirubin.

关 键 词：肌酸激酶同工酶 胆红素 婴儿 新生 

分 类 号：R722.1[医药卫生—儿科]