防芷鼻炎片中5-O-甲基维斯阿米醇苷的含量测定  

Determination of 5-O-Methylvisammioside in Fangzhibiyan Tablets by HPLC

作　　者：钟一雄 李战 曾玲 

机构地区：[1]广西玉林制药有限责任公司,广西玉林537001

出　　处：《中国药业》2008年第14期41-42,共2页China Pharmaceuticals

摘　　要：目的用高效液相色谱(HPLC)法测定防芷鼻炎片中5-O-甲基维斯阿米醇苷含量。方法采用Zorbax SB-C18色谱柱(4.6mm×250mm,5μm),流动相为甲醇-水(40∶60),检测波长为254nm。结果5-O-甲基维斯阿米醇苷进样量线性范围为0.10～0.90μg,平均加样回收率为100.23%,RSD为1.28%(n=6)。结论HPLC法简便可行、结果可靠,可以控制防芷鼻炎片的质量。Objective To set up a method for determining the 5- O-methylvisammioside in Fangzhibiyan Tablets. Methods Zorbax SB- C18 column（4.6 mm ×250 mm, 5 μm）was used, The mobile phase was methanol-H2O（40：60）, the detecting wavelength was at 254 nm. Results The standard curve was linear within a range of 0. 10-0.90 pLg. The average recovery rate and RSD were 100. 23% and 1.28% （n =6）, respectively. Conclusion This method is accurate, reliable. It can provide the scientic index for the quality control of Fangzhibiyan Tablets.

关 键 词：防芷鼻炎片 5—O-甲基维斯阿米醇苷 高效液相色谱法 含量 

分 类 号：R286.0[医药卫生—中药学] R284.1[医药卫生—中医学]