肌肉因素与骨关节炎的临床研究现状  

Clinical advances of muscle status in osteoarthritis

作　　者：曹月龙[1] 庞坚[1] 詹红生[1] 石印玉[1] 

机构地区：[1]上海中医药大学附属曙光医院骨伤科,上海201203

出　　处：《中国骨伤》2008年第6期476-479,共4页China Journal of Orthopaedics and Traumatology

基　　金：国家自然科学基金(编号:30300459)

摘　　要：本文主要从临床角度对肌肉因素在骨关节炎(OA)的发病及治疗中的情况作一综述。多项研究说明肌肉软弱、肌力下降及肌肉功能状态改变在OA病理过程中的重要性,提示肌肉也是骨关节炎治疗的有效靶标之一。因此,从调控肌肉因素的角度来研究骨关节炎病理机制及研发治疗药物值得进一步展开。This article summarizes relevant clinical studies on muscle status and osteoarthritis. Evidence from many researches have implied the importance of muscle weakness, decreased muscle strength and muscle function as pathological factor in the process of osteoarthritis, and muscle should also be an effective target for the treatment of osteoarthritis. Further study need to be conducted from the angle of muscle to explore the mechanism of osteoarthritis and to develop new drugs.

关 键 词：肌肉骨骼平衡 骨关节炎 病理过程 综述文献 

分 类 号：R684.3[医药卫生—骨科学] R681[医药卫生—外科学]