二硫化碳作业工人的肾功能观察  

Observation of Renal Function in Carbon DisulfideExposed Workers.

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作  者:陈苘[1,2] 胡迪生[1,2] 简乐[1,2] 曹文俊 张国军[1,2] 

机构地区:[1]浙江医科大学公共卫生学院 [2]杭州市职业病防治院

出  处:《中国工业医学杂志》1997年第6期325-327,共3页Chinese Journal of Industrial Medicine

摘  要:目的:探讨二硫化碳(CS2)对作业工人肾功能的影响及其与脂质过氧化的可能联系。方法:对94名CS2作业工人和53名不接触CS2及其他毒物者进行尿蛋白、尿酶、LPO及SOD的观察,以非参数统计K-W法和等级相关法进行数据分析。结果:CS2作业工人尿AKP活性和红细胞LPO较对照组明显升高(P<0.01)。To observe the influences of carbon disulfide on kidney and the relationship between its nephrotoxicity and lipid peroxidation,94 workers exposed to CS2 and 53 controls were investigated,their urine protern and enzyme,erythrocyte LPO and SOD were determined in the study.Data were analyzed with NPAR KW test and rank correlation method.Results showed that the urine AKP and erythocyte LPO in CS2 exposed workers were significantly increased(P<0001).It was suggested that CS2 might increase free radical production in living cells which might induce slight damage in kidney.

关 键 词:二硫化碳 肾功能 尿酶 过氧化脂质 超氧化物歧化酶 

分 类 号:R135.1[医药卫生—劳动卫生] R994.3[医药卫生—公共卫生与预防医学]

 

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