中药对冠心病患者脂质过氧化速率、微量元素及脂质代谢的影响  

Effect of traditional chinese medicine on the rate of lipid Peroxidation. Lipid metabolism and the serum levels of trace elements in petients with coronary heart disease

作　　者：魏重琴[1] 艾建芳 付蕾[1] 王清云[2] 孙红光[2] 王旗[3] 

机构地区：[1]河南医科大学生化教研室 [2]河南中医学院 [3]河南医科大学营养卫生教研室

出　　处：《河南医科大学学报》1990年第4期362-366,共5页Journal of Henan Medical University

摘　　要：对92例冠心病患者多项生化指标进行测定,观察患者服用中药“心脑维新”前后体内脂质过氧化速率、微量元素及脂质代谢的变化。结果:疗后红细胞超氧化物质歧化酶(SOD)比活性,高密度脂蛋白胆固醇(HDL-CH)含量明显提高(P值均<0.001),血浆过氧化脂质(LPO)、血清总胆固醇(T-ch)及甘油三酯(TG)浓度、血清异柠檬酸脱氢酶(ICD)活性、血浆微量元素(Cu,Zn,Fe)含量显著下降(P值均<0.05)。提示该中药具有明显的抑制脂质过氧化和抗衰老作用,并能调节微量元素及脂质代谢。The study reported the effect of oral administration the traditional Chinesemedicine.Xin Nao wei Xin, On the rate of lipid peroxidation and lipid metabolis-m in vivo and the serum levels of some of the trace elements in 92 patients withcoronary heart disease (CHD). The result showed that after the treatment withthis medicine, the specific activity of erythrocyte superoxide dismutase (SOD)and the serum level of high density lipoprotein cholesterol (HDL-ch) and theconcentration of the triglycerde (TG). the total cholesterol (T-ch), and the conte-nts of some of the trace elements.such as Cu. Zn and Fe were decreased as com-pared with those of the patients with CHD before treatment. However,the serumlevel of low density lipoprotein cholesterol (LDL-ch)was also lowered, but nostatistical significance was noticed.The contents of some trace elements as me-nt ioned above were not changed in hair before and after the treatment with themedicine.

关 键 词：中药 冠心病 脂质过氧化 微量元素 

分 类 号：R286.23[医药卫生—中药学]