非中心性肥胖患者代谢综合征危险因素与体质量及腰围的关系  

Relationship of body mass index and waist circumference with metabolic syndrome risk factors in non-centricity obesity patients

作　　者：伊力哈木江.依马木 谢自敬[1] 毛新民[1] 李琳琳[1] 

机构地区：[1]新疆医科大学第一附属医院内分泌科,新疆维吾尔自治区乌鲁木齐市830011

出　　处：《中国组织工程研究与临床康复》2008年第28期5571-5576,共6页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金："新疆2型糖尿病遗传资源库及相关基因研究"新疆维吾尔自治区科技攻关和重点科技项目(200633129);"新疆维吾尔族MODY基因表现型初步研究;维吾尔族成人早发2型糖尿病家系的比较代谢学研究"新疆医科大学第一附属医院科研启动基金(XJDX0208-2006-06);"遗传因素与环境因素相互作用在新疆维吾尔族糖尿病发病中作用的家系研究"国家自然科学基金项目(30560055);新疆维吾尔族糖尿病高发的家系研究新疆维吾尔自治区自然科学基金项目(200421124)~~

摘　　要：背景:2005年国际糖尿病联盟修改代谢综合征诊断标准时,把腰围作为诊断代谢综合征的必备条件,这一改变对中国代谢综合征的诊断是否有影响还需进一步调查分析。目的:分析非中心性肥胖患者体质量和腰围与代谢综合征危险因素的关系。设计、时间及地点:横断面调查及描述性研究,于2002-04/2005-09在乌鲁木齐及哈什地区完成调查。对象:共计5340人,其中维吾尔族2623人,汉族2716人。①整群抽样调查乌鲁木齐市新市区农机厂工人及社区汉族居民共3000人,其中资料完整的2716人,男1664人,女1052人,年龄26～86岁。②多级整群抽样调查喀什市及周边县与乡的维吾尔族居民2876人,其中资料完整者共计2623人,男990人,女1633人,年龄25～90岁,包括政府机构工作人员、公安干警、教师、农民、自由职业者及从事家务劳动者。方法:问卷调查包括年龄、性别、族别、婚姻、职业、劳动性质、劳动强度、人均收入、文化水平、饮酒史、吸烟史、糖尿病史及家族史、高血压史及家族史等。同时进行2型糖尿病相关因素危险因素的问卷调查。主要观察指标:受试者测定血压、体质量指数、臀围,取血化验血糖、三酰甘油、高密度脂蛋白胆固醇水平。结果:①维吾尔族男性除舒张期血压和高密度脂蛋白胆固醇外,其他所有指标都随着腰围的增加与加重;除空腹血糖≥7.0mmol/L的切点外,体质量指数与其他所有变量的切点间不相关。②维吾尔族女性除三酰甘油与体质量指数的切点相关外,其他所有指标的切点无论与体质量指数还是腰围之间均没有关系。③汉族男性无论什么指标切点都与腰围有明显的关系;除空腹血糖≥6.1mmol/L的切点及高密度脂蛋白胆固醇的切点与体质量指数间没有关系外,其他指标的切点也都与体质量指数有显著的关系。④汉族女性除空腹血糖≥6.1mmol/L的切点及高密度脂�BACKGROUND： Waist circumference is added in diagnostic criteria of metabolic syndrome of International Diabetes Federation in 2005. Whether this change influences the diagnosis of metabolic syndrome needs further investigation. OBJECTIVE： To study the relationship of body mass and waist circumference with metabolic syndrome risk factors in non-centricity obesity patients. DESIGN, TIME AND SETTING： Cross-sectional study and descriptive study were performed at Urumchi and Hashi from April 2002 to September 2005. PARTICIPANTS： 5 340 people were selected, including 2 623 Uygur population and 2 716 Hans. Using cluster sampling method, 3 000 Han population was selected from workers of farm machinery factory and communities of Xinshi District, Urumchi, and 2 716 had complete data, including 1 664 males and 1 052 females aged 26-86 years. In addition, 2 876 Uygur population was selected from Keshi and surrounding county and town, and 2 623 had complete data including 990 males and 1 633 females aged 25-90 years. They were staff of government, polices, teachers, farmers, free professional and house workers. METHODS： The content of questionnaire included age, gender, nationality, marriage, occupation, labour quality, labour intensity, per capita income, drinking, smoking, diabetes and family history, hypertension and family history. In addition, type 2 diabetes-related risk factors were investigated. MAIN OUTCOME MEASURES： Blood pressure, body mass index （BMI） and hip circumference were measured. In addition, blood sugar, triglyceride, and high-density lipoprotein cholesterol levels were determined. RESULTS： In Uygur male, except diastolic blood pressure and high density lipoprotein cholesterol, all indexes increased with increase in waist circumference. Except fasting glucose ≥ 7.0 mmol/L point, BMI did not relate with other variable points. In Uygur female, only triglyceride had relationship with BMI and none other indexes had relation with waist circumference or BMI. In Han male, all targ

关 键 词：代谢综合征 危险因素 腰围 体质量指数 

分 类 号：R589[医药卫生—内分泌]