广州地区3个鸭种1日龄雏鸭垂直感染鸭乙肝病毒调查  

Study on Vertical Infection of DHBV in Three Kinds of Ducklings in Guangzhou

作　　者：邓学龙[1,2] 朱宇同[1,2] 方宏勋 容秉培[1,2] 郭兴伯 王新华[1,2] 刘妮 符林春[1,2] 

机构地区：[1]广州中医药大学热带医学研究所 [2]香港城市大学

出　　处：《广州中医药大学学报》1997年第4期274-276,共3页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医药管理局科研基金

摘　　要：鸭乙型肝炎病毒（ＤＨＢＶ）与人乙型肝炎病毒（ＨＢＶ）同属嗜肝ＤＮＡ病毒科，ＤＨＢＶ感染的鸭，可造成为较好的ＨＢＶ动物模型和作为嗜肝病毒科分子病毒学研究的材料。为查明不同鸭种的垂直感染情况，本文采用斑点杂交方法对广州地区３个主要鸭种１日龄雏鸭携带鸭乙型肝炎病毒（ＤＨＢＶ）进行了调查，广州麻鸭１日龄ＤＨＢＶＤＮＡ阳性率为１４／５０（２８％），樱桃谷鸭１日龄为２／１０（２０％），野水鸭１日龄为８／１０（８０％）。提示野水鸭垂直感染率最高，对追踪ＤＨＢＶ基因同源性和基因变异提供了良好的材料。おuck hepatitis B virus (DHBV) shares the same hepatophilic DNA virus family with human hepatitis B virus (HBV). The duck infected with DHBV may serve as the animal model of HBV for the virologic study of hepatophilic viral molecule to study the vertical infection of DHBV in different kinds of ducks. Three kinds of ducklings carrying DHBV in Guangzhou city were investigated with method of dot blot hybridization technique. The incidences of DHBV carriers among Guangzhou duckling, Cherry valley duckling and wild water duckling were 28%,20%and 80% respectively, the wild water duck being the highest. This may provide a good material for the study of homogeneity and variability of DHBV gene.

关 键 词：鸭肝炎病毒 杂交 动物模型 乙型肝炎 

分 类 号：R512.62[医药卫生—内科学]