通光藤的化学成分研究  

Chemical constituents of Marsdenia tenacissima

作　　者：石慧[1] 崔炯谟[1] 关健 赵余庆[3] 

机构地区：[1]延边大学药学院,吉林延吉133000 [2]辽宁省医药工业研究院,辽宁沈阳110015 [3]沈阳药科大学,辽宁沈阳110016

出　　处：《中草药》2008年第7期970-972,共3页Chinese Traditional and Herbal Drugs

摘　　要：目的研究通光藤Marsdenia tenacissima的化学成分。方法利用硅胶、Dephadex LH-20等各种色谱技术进行分离纯化,根据化合物的理化性质和光谱数据进行结构鉴定。结果从通光藤的正丁醇层提取物中分离得到6个化合物,分别鉴定为二氢肉珊瑚苷元(Ⅰ)、胡萝卜苷(Ⅱ)、3-O-乙酰基-齐墩果烷-18-烯-3β-羟基(3-O-acetyl-oleanane-18-ene-3β-ol,Ⅲ)、牛奶菜醇(Ⅳ)、β-谷甾醇(Ⅴ)、豆甾醇(Ⅵ)。结论化合物Ⅰ为首次从自然界中分离得到的新天然产物,化合物Ⅱ为首次从该植物中分得。Objective Various chromatographic To study the chemical techniques were employed constituents of Marsdenia tenacissima. Methods for the isolation and purification of the constituents, such as silica gel and Sephadex LH-20, etc. Results Six compounds were isolated from n-butyl alcohol layer of M. tenacissirna and their structures were identified as dihydrosarcostin （ Ⅰ ）, daucosterol （Ⅰ）, 3- O-acetyl-oleanane-18-ene-3β-ol （Ⅲ）, condutirol （Ⅳ）, β-sitosterol （V）, and stigmasterol （Ⅵ）. Conclusion For the first time, compound Ⅰ is found as a natural product in this plant and compounds Ⅰ-Ⅱ are isolated from this plant.

关 键 词：通光藤 二氢肉珊瑚苷元 胡萝卜苷 

分 类 号：R284.1[医药卫生—中药学]