免疫不孕患者自身抗体检测结果分析  

Analysis of the Results of Determining Autoantibodies in Patients with Immunological Infertility

作　　者：陈桂冰[1] 黄绍坤[1] 赵香生[1] 张然[1] 

机构地区：[1]广东省深圳市中医院,518033

出　　处：《职业与健康》2008年第16期1725-1726,共2页Occupation and Health

摘　　要：目的了解深圳地区不孕不育患者的免疫不孕的因素。方法对3216例不孕不育患者用酶联免疫吸附试验(ELISA)联合检测血清中抗精子抗体(AsAb)、抗子宫内膜抗体(EmAb)、抗卵巢抗体(AoAb)、抗绒毛膜抗体(HCGAb)、抗滋养层抗体(ATAb)、抗心磷脂抗体(ACAb)、抗透明带抗体(AzpAb)。结果652例男性的AsAb阳性率为25.73%,2564例女性中7种抗体的阳性率分别为23.06%、20.00%、6.74%、11.35%、7.21%、14.74%和7.60%。结论免疫性原因是大部分不明原因继发性不孕不育和反复流产的主要原因。[ Objective] To investigate the immunologic factors of infertile patients in Shenzhen city. [ Methods ] Sera AsAb, EmAb, AoAb, HCGAb, ATAb, ACAb and AzpAb of 3216 cases of infertile patients were detected by ELISA. [ Results ] AsAb positive rate in 652 male patients was 25.73%, and in 2564 male patients positive rates of the 7 antibodies was 23.06%, 20.00% ,6.74%, 11.35%, 7.21%, 14.74% and 7.60% respectively. [ Conclusion] immunological factors are the main factors affecting unex plained continue infertile and recurrent abortion.

关 键 词：不孕不育 抗精子抗体 抗子宫内膜抗体 抗卵巢抗体 抗绒毛膜抗体 抗滋养层抗体 抗心磷脂抗体 抗透明带抗体 

分 类 号：R446.6[医药卫生—诊断学]