正交试验优化积雪草总苷提取工艺  

Optimization of the Extraction Process of Asiaticoside by Orthogonal Experiment

作　　者：张开莲[1] 张炜[1] 

机构地区：[1]泸州医学院药学院,泸州市646000

出　　处：《中国药房》2008年第21期1618-1620,共3页China Pharmacy

基　　金：四川省教育厅重点课题(川教函2003407;2003A052)

摘　　要：目的:优化积雪草中积雪草总苷的提取工艺。方法:以积雪草总苷提取率为评价指标,采用单因素试验与正交试验优选积雪草中积雪草总苷的提取条件。结果:积雪草总苷的最优提取工艺为乙醇浓度60%,料液比1:12,超声提取1h。结论:该提取方法简单可行,可使积雪草总苷提取率较高。OBJECTIVE： To optimize the extraction process of Asiaticoside. METHODS： The extraction techaique was optimized by single factor test and orthogonal design taking extraction rate of Asiaticoside as the indicator. RESULTS： The best extracting technical conditions were as follows： ultrasonically extracting 12 times amount of 60% ethanol for an hour. CONCLUSION： The extraction method is simple and feasible and by which high extraction rate of Asiaticoside was obtained.

关 键 词：积雪草总苷 提取工艺 单因素试验 正交试验 

分 类 号：R283[医药卫生—中药学] R94[医药卫生—中医学]