综合疗法治疗尖锐湿疣的疗效观察  

Observation on the efffect of comprehensive treatment of condyloma acuminatum

作　　者：邵奕[1] 李卫红[1] 

机构地区：[1]茂名市人民医院,广东茂名525000

出　　处：《中国热带医学》2008年第8期1329-1330,1332,共3页China Tropical Medicine

摘　　要：目的寻找减少尖锐湿疣复发的治疗方法。方法将符合入选标准的60例患者随机分两组，两组患者均行电灼术，清除全部皮损，治疗组联合α-2b干扰素局部注射及聚维酮碘乳膏外涂，对照组单行电灼术。结果治疗组复发率13．33％，对照组36．67％，两组比较X^2=7.5766，P〈0．01；治疗前后免疫功能检测各项结果比较。治疗组t=3．0988-5．8396，P〈0．01；治疗组与对照组组间比较，t=2．7297-5．3724，P〈0．01。治疗组医患双方耐受性评价比较，U=1．2061，P=0．2191；对照组医患双方两组耐受性评价，U=1．2643，P=0．1976；两组耐受性比较，U=1．3186，P=0．1905。两纽不良反应率比较，x^2=3．3795，P=0．0661。结论本综合疗法对尖锐湿疣患者是安全有效的。Objective To find a therapeutic way that can reduce the recurrence of condyloma acuminatum infection. Methods There 60 condyloma acuminatum patients underwent electrocautery and removed all skin lesions were randomly divided into treatment groups and treated with interferon α-2b injections plus external application of povidone iodine cream and control group only treated with single electrocautery. Results Recurrence rate of the treatment group was 13.33%, yet 36. 67% in control group, showing significant statistical difference （X^2= 7.5766, P 〈 0.01 ） ; the indexes of immune function in the treatment group before and after the treatment were t = 3.0988-5.8396 and t = 2.7297-5.3724, and control group, showing signficant differences （ P 〈 0.01） . The results of tolerance evaluation of doctor - patient in the treatment group were, U =1.2061, P=0.2191 and U = 1.2643, P = 0. 1976 in the control group, without significant differences between the tw ogroups （ U = 1.3186, P = 0. 1905 ）. Conclusion The combined therapy for treatment of patients with condyloma acumina-turn is safe and effective.

关 键 词：尖锐湿疣 电灼术 重组人干扰素α-2b注射液 聚维酮碘乳膏 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]