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作 者:张树栋[1] 马潞林[1] 王国良[1] 侯小飞[1] 罗康平[1] 赵磊[1]
机构地区:[1]北京大学第三医院泌尿外科,北京市100083
出 处:《中国组织工程研究与临床康复》2008年第31期6133-6136,共4页Journal of Clinical Rehabilitative Tissue Engineering Research
摘 要:回顾性分析于2001—01/2005—07在本院行同种异体肾移植术615例患者的临床资料,总结本院肾移植术后外科并发症的发生原因、处理经验与教训。男347例,女268例,年龄9~75岁,体质量38—100kg。脑死亡供体采用原位低温灌注改良切取法取肾,活体供肾采用后腹腔途径开放或腹腔镜切取,进行肾移植手术。移植术后采用以FK506或环孢素A为主的三联免疫抑制剂治疗,免疫抑制剂的剂量根据血药浓度进行调整。术后随访1年,615例肾移植患者中共发生各种外科并发症29例,发生率为4.72%。由于外科并发症导致移植肾丢失5例,手术成功率为99.19%。We retrospectively analyzed the clinical data of 615 recipients (347 male and 268 female, age range: 9-75 years, weighing 38-100 kg) who received renal transplantation in the Third Hospital of Peking University from January 2001 to July 2005 to summarize the causes and experience of surgical complications after renal transplantation. Kidney of donors with brain death was obtained using modified in situ hypothermy perfusion method, and kidney from living bodies was obtained using posterior abdominal cavity open or abdominal speculum method. After renal transplantation, the immunosuppressive therapy including FKS06 or Cyclosporine A + mycophenolate mofetial or mizoribine + Prednisone was applied and regulated according to the variation of concentration in whole blood. Recipients were followed up for at 1 year. Of 615 patients, 29 cases developed surgical complications with the incidence rate of 4.72%; Graft lost in 5 cases due to surgical complications after renal transplantation. The achievement ratio of operation was 99.19%.
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