棕色田鼠胃肠道5-羟色胺细胞的免疫组织化学定位  

Immunohistochemical Localization of 5-HTIR Cells in Gastrointestinal Tract of Mandarin Vole Microtus mandarinus

作　　者：李丽霞[1] 胡佳[1] 

机构地区：[1]陕西理工学院,陕西汉中723001

出　　处：《四川动物》2008年第4期639-641,661,共4页Sichuan Journal of Zoology

基　　金：陕西理工学院科研基金资助项目(No.SLG0520)

摘　　要：应用ABC免疫组织化学方法,对棕色田鼠胃肠道内5羟-色胺细胞进行了免疫组织化学定位和形态学观察。结果表明:5-HTIR细胞在棕色田鼠胃肠道的各段均有分布,其中以十二指肠和直肠段分布密度最高,胃底、胃幽门部、空肠、回肠、盲肠段其次,胃贲门部、胃体、结肠段分布密度最低。5羟-色胺细胞位于胃腺上皮、肠粘膜上皮、肠腺上皮及固有膜,有圆形、椭圆形、梭形、楔形和不规则形,有的还具有胞突。对棕色田鼠胃肠道5-HTIR细胞的分布、形态与功能相适应的特点进行了讨论。Immunohistochemical localization and morphology of 5-hydroxytryptamine immunoreactive cells （5-HTIR cells） in the gastrointestinal tract of mandarin vole Microtus mandarinus were investigated by ABC immunostaining tech- nique. The results showed that 5-HTIR cells distributed throughout the gastrointestinal tract and located in the gastric glands of the stomach regions and in the intestinal or esophageal epithelium with variable frequencies. The highest density of the 5- HTIR cells was in the duodenum and rectum, and higher in the fundus of stomach, pyloric part, jejunum, ileum, and ce- cum, and the lowest in the cardiac part, body of stomach and colon. The 5-HTIR cells were in various shapes, such as round, oval, spindle-like, wedge-like or irregular in shape. And some of the 5-HTIR cells had processes. The distribution mode of 5-HTIR cells and the characteristics adapted to morphology and function of the 5-HTIR cells are discussed in this paper.

关 键 词：棕色田鼠 胃肠道 5-HTIR细胞 免疫组织化学定位 

分 类 号：Q954.6[生物学—动物学]