异丙酚诱导麻醉对血液动力学的影响  

Effect of Propofol on Adult Haemodynamics

作　　者：任永功[1] 王明玲[1] 李士通[1] 曾邦雄[1] 

机构地区：[1]同济医科大学附属协和医院麻醉科,武汉430022

出　　处：《同济医科大学学报》1997年第6期482-484,共3页Acta Universitatis Medicinae Tongji

摘　　要：11例择期神经外科手术患者应用异丙酚诱导麻醉，对比诱导前后，插管后血液动力学的改变和机体对气管插管的应激反应。结果表明：动脉收缩压（SBP）诱导后明显下降（P＜0.05），舒张压（DBP）和平均动脉压（MAP）亦是如此；气管插管后血压迅速回升，并超过诱导前水平（P＜0．05），说明异丙酚对插管引起的应激反应抑制不明显。搏出量（SV）、左室每搏动指数（LVSWI）诱导后明显降低（P＜0．05），因此，对循环功能不稳定患者应用异丙酚宜以小剂量复合用药。In 11 adult patients scheduled for neurosurgery, anesthesia was induced with propofol andtracheal intubation was carried out. Haemodynamic changes after induced anesthesia and stress response totracheal intubation were compared to those before anesthesia. Results showed that systolic, diastolic andmean blood pressure decreased significantly (P<0. 05) after propofol induced anesthesia, respectively.After tracheal intubation, blood pressure increased rapidly and characteristically excessed hasal blood pressureP <0. 05). The results indicated that propofol had little inhibition effect on stress response to trachealintubation. Stroke volume (SV) and left ventricular stroke work index (LVSWI) decreased significantly (P <0. 05) after induced anesthesia. The changes of SV and LVSWLI demonstrated that low dosage of propofolcombined with other medicine should be given to patients with unstable haemodynamics.

关 键 词：异丙酚 麻醉 静脉内 血液动力学 

分 类 号：R331.3[医药卫生—人体生理学]