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作 者:张立君[1] 孙辉[1] 徐伯楠[1] 邓晶[1] 侯杰[1] 郭子丹[1] 孙亚非[1] 王晓亚[1] 王铜[1]
机构地区:[1]哈尔滨医科大学中国疾病预防控制中心地方病控制中心克山病防治研究所,150081
出 处:《中国地方病学杂志》2008年第4期425-427,共3页Chinese Jouranl of Endemiology
基 金:卫生部疾病控制司委托项目(2007)
摘 要:目的了解2007年克山病监测点黑龙江省富裕县永进村人群患病、发病情况及内外环境的硒水平。方法按全国克山病监测方案及《克山病诊断标准》(GB17021—1997),对监测点区居民进行临床查体和心电图描记,可疑心脏异常者行X线胸部摄片;采集当地部分儿童头发和食用粮样(面粉),氢化物发生原子荧光法测定含硒量。结果2007年在永进村共检诊282人.检出克山病19例,总检出率6.7%。其中潜在型克山病8例(有5例为新检出),慢型克山病11例,检出率分别为2.8%、3.9%。另外,还检出可疑克山病5例.其中可疑慢型2例,未检出急型、亚急型克山病病例。儿童发硒为(0.3197±0.0586)mg/kg;粮食硒为(0.0210±0.0062)mg/kg。结论永进村仍有新的克山病病例检出,说明病区仍有致病因素存在,因此.在病区建立完善的克山病监测疫情报告系统.提高各级防治人员对克山病的认识.仍是今后克山病防治的重点.Objective To investigate the prevalence and incidence of Keshan disease (KD) and the selenium concentration of food and hair in residents of Yongjin Village, Fuyu County, Heilongjiang Province, national monitoring site, in 2007. Methods According to the Standard of Keshan Disease Surveillance and the Standard of Diagnosis of Keshan Disease(GB 17021-1997), the residents living in the monitoring site were surveyed by clinical examination and electrocardiography. For individuals whose hearts showed abnormalities, a chest X-ray photograph was taken. The selenium concentrations of the residents' food (flour) and hair were assayed by flowing injection hydride generation atomic fluorometric method (FI-HG-AFM). Results Nineteen KD patients were found from 282 residents in 2007 KD surveillance. The prevalence of KD, latent KD and chronic KD were 6.7%(19/282), 2.8%(8/282) and 3.9%(11/282), respectively. Five of the 8 latent KD cases were newly found. In addition, there were 5 the suspected KD cases, including 2 suspected chronic KD cases. No acute KD or sub-acute KD patients were found in Yongjin Village at this monitoring site this year. The average selenium concentration of children hair and residents food were (0.3197 ± 0.0586)mg/kg and (0.0210 ± 0.0062)mg/kg, respectively. Conclusions New cases of KD continued to emerge, indicating that etiological factors still exist. Therefore, the emphasis of monitoring KD in future is founding the consummate report of infectious disease system and training the personnel to increase the reliability of monitoring.
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