2007年陕西省甘泉县克山病病情分析  

Analysis of Keshan disease prevalence in Ganquan County of Shaanxi Province in 2007

作　　者：何新科[1] 杨杰[1] 徐刚要[1] 陈平[1] 吕晓亚[1] 郑来义[1] 邓建霞[1] 刘慧兰[1] 李国栋[2] 安薇[2] 连维和 

机构地区：[1]陕西省地方病防治研究所克山病大骨节病防治研究室,西安710003 [2]陕西省延安市疾病预防控制中心 [3]陕西省甘泉县疾病预防控制中心

出　　处：《中国地方病学杂志》2008年第4期428-430,共3页Chinese Jouranl of Endemiology

基　　金：中央补助地方公共卫生专项资金地方病防治项目（2006）

摘　　要：目的掌握陕西省甘泉县克山病病情消长趋势和现状，为科学指导和评价防治工作，巩固已取得的防治成果提供依据。方法按照全国克山病病情监测方案要求，2007年对甘泉县劳山乡大劳山村和小劳山村居民进行填表登记，询问病史，测量血压，进行临床体格检查和心电图描记；慢型克山病及疑似克山病病人拍摄2m后前位X线胸片，并采集发样、粮样，用2，3-二氨基萘荧光法进行含硒量测定。结果临床检出潜在型克山病20例，检出牢为2．67％（20／749）；慢型克山病1例，检出率为0．13％（1／749）。描记心电图749例，检出异常心电图82例，检出率为10．95％（82／749）。16例慢型克山病及疑似克山病病人测定心胸比例，结果正常9例、轻度扩大3例、中度扩大2例、重度扩大2例。发硒均值为（0．335±0．102）mg／kg，小麦硒均值为（0．045±0．019）mg／kg，小米硒均值为（0．029±0．017）mg／kg。结论甘泉县经过以补硒为主的综合性预防措施后，全县无急型、亚急型克山病发生，克山病病情呈稳定下降趋势，潜、慢型克山病是目前患病的主要形式和存在类型。Objective To master th＇e Keshan disease situation, guide and evaluate Keshan disease control work scientifically, and consolidate the control achievements in Ganquan County of Shaanxi Province. Methods According to the scheme of National Keshan Disease Surveillance, the residents were surveyed including the case history, blood-pressure, electrocardiogram and X-ray examinations for chronic and suspected cases. Levels of selenium in hair and grain were determined by the diaminonaphthalene method. Results Twenty latent and one chronic Keshan disease patients were detected, accounting for 2.67%（20/749） and 0.13% （1/749）, respectively, of surveyed residents in Laoshan Village. Electrocardiography showed abnormalities in 82 of the 749 surveyed individuals（10.95%）. The heart-chest ratio was increased in seven of 16 chronic or suspected Keshan disease patients. The content of selenium in hair, wheat and millet was （0.335 ± 0.102）, （0.045 ± 0.019）, （0.029 ± 0.017）mg/kg, respectively. Conclusions Keshan disease prevalence showed a stable and decreasing tendency due to the general control measures, especially supplementation of selenium in food in Ganquan County. No acute or subacute Keshan disease occurred. Currently, latent and chronic Keshan diseases are the main types of Keshan disease.

关 键 词：克山病 心电描记术 X线 硒 

分 类 号：R686[医药卫生—骨科学]