血小板、血沉和C反应蛋白与川崎病患儿冠状动脉损伤的关系  

Relationship of platelet,erythrocyte sedimentation rate and C reactive protein with coronary artery lesions in Kawasaki disease patients

作　　者：邓素娟[1] 朱美华[1] 

机构地区：[1]广州医学院第二附属医院

出　　处：《现代中西医结合杂志》2008年第23期3574-3575,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的探讨血小板、血沉和C反应蛋白(CRP)与川崎病患儿冠状动脉损伤的关系。方法对47例川崎病患儿在治疗前和治愈后进行外周血血小板计数、血沉和血清CRP检测,并通过心脏彩色多普勒超声检查明确患儿冠状动脉损伤情况。结果川崎病患儿在急性发病时血小板计数、血沉和血清CRP均明显升高;治愈后基本恢复到正常水平。伴有冠状动脉损伤的川崎病患儿血小板计数、血沉和血清CRP明显高于不伴冠状动脉损伤的患儿。结论川崎病外周血血小板计数、血沉和血清CRP的升高程度与患儿急性炎症反应程度密切相关,同时也可作为预测患儿冠状动脉病变的重要指标。Objective It is to discuss the relationship of platelet （Plt）, erythrocyte sedimentation rate （ESR） and C reactive protein （CRP） with coronary artery lesions in Kawasaki disease patients. Methods The levels of Plt, ESR and CRP in 47 Kawasakl disease patients before and after treatment were detected. The coronary artery lesions were checked with heart color Doppler ultrasound. Results The levels of Plt, ESR and CRP in Kawasaki disease patients were obviously heightened at acute phase and recovered to normal after treatment. The levels of Plt, ESR and CRP in Kawasaki disease patients with coronary artery lesions were obviously higher than that without coronary artery lesions. Conclusion The heightening degree of Plt, ESR and CRP in Kawasaki disease patients has close relation with the degree of acute inflammation reaction. They can be used as the important index of predicting coronary artery lesions in Kawasaki disease patients.

关 键 词：川崎病 冠状动脉 血小板 血沉 C反应蛋白 

分 类 号：R725.5[医药卫生—儿科]