钯碳催化下以甲酰肼为还原剂的卤代芳烃还原偶联反应研究  

Pd/C-Catalyzed Reductive Coupling of Aryl Halides Using Formic Hydrazide as Reducing Agent

作　　者：朱雯芳[1] 乔江彬[1] 卓广澜[1] 

机构地区：[1]浙江理工大学应用化学系,杭州310018

出　　处：《有机化学》2008年第7期1259-1263,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20476092)资助项目

摘　　要：在Pd/C催化下,以甲酰肼为还原剂,卤代芳烃通过还原偶联反应能高选择性地合成相应的联苯化合物.具有不同取代基的卤代芳烃的还原偶联反应产率在52%～94%之间.The reductive coupling of aryl halides to form the corresponding biaryls was effected with high selectivity in water, using formic hydrazide as a reducing agent in the presence of a catalytic amount of Pd/C. Various substituted aryl halides proceed smoothly to afford the corresponding biaryls with good yields in the range of 52%-94%.

关 键 词：联苯衍生物 卤代芳烃 甲酰肼 PD/C 还原偶联反应 

分 类 号：O643.32[理学—物理化学]