中医证候模型拟临床研究概念的形成及应用  

Definition and application of clinical-mimetic research in animal models with syndromes of Chinese medicine

作　　者：刘建勋[1] 李欣志[1] 任建勋[1] 

机构地区：[1]中国中医科学院西苑医院实验研究中心,北京100091

出　　处：《中国中药杂志》2008年第14期1772-1776,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金重大研究计划(90709001);国家"十一五"科技支撑计划(2006BAI08B01-06)

摘　　要：通过近年来的探索性研究,结合有关中医证候模型的文献研究,分析现有中医证候模型研究中存在的问题,提出中医证候模型拟临床研究的概念,并对其可能的应用价值进行评述。提倡用临床实验方法研究中医证候的科学规律及其演化过程,并对病证结合模型动物进行中药干预,评价药物的对证候模型的作用及内在本质,构建符合中医药作用的特点药物评价技术及研究平台。On the base of reviewing the current literatures concerning the animal models with syndromes of Chinese medicine and investigating thee present state of the syndrome models, the authors have put forward a definition that research of animal models with the syndromes of Chinese medicine should be combined with clinical methods, and commented the potential application. Further it was suggested that clinical methods should be used in the exploration of scientific principles and the progresses on syndromes of Chinese medicine. In addition, intervene and evaluation of Chinese herbal medicine in animal model with integrated diseases and syndromes should be emphasized to establish a platform with special properties of TCM

关 键 词：证候 疾病模型 拟临床研究 病证结合 

分 类 号：R241[医药卫生—中医诊断学]