人类免疫缺陷病毒感染/艾滋病合并分枝杆菌肺病133例临床分析  

A clinic analysis of 133 cases HIV infection/AIDS combinated with mycobacterial pulmonary disease on divarication bacilli

作　　者：蒙志好 张福杰[2] 刘存旭 杨日耀 李虹如 于兰[2] 王黎明[2] 

机构地区：[1]广西壮族自治区龙潭医院内七科,广西柳州545005 [2]中国疾病预防控制中心性病艾滋病预防控制中心

出　　处：《临床内科杂志》2008年第7期478-480,共3页Journal of Clinical Internal Medicine

基　　金：广西壮族自治区卫生厅项目(Z2006131);克林顿基金会

摘　　要：目的探讨人类免疫缺陷病毒（HIV）感染/艾滋病（AIDS）合并分枝杆菌病的临床特点、诊断和治疗方法。方法对2006年10月~2007年9月住院的HIV/AIDS合并分枝杆菌病患者的临床资料进行分析。结果人类免疫缺陷病毒感染/艾滋病合并分枝杆菌肺病以发热和咳嗽为主要表现,结核病约占2/3,非结核分枝杆菌（NTM）病约占1/3,其中肺结核78例,淋巴结结核26例,同时伴有两个部位以上结核者30例。CD4＋T淋巴细胞平均值为55×106/L,胸片异常93例,痰抗酸杆菌涂片阳性17例,培养阳性57例,经治疗后总死亡率为9.8%。结论HIV/AIDS合并分枝杆菌感染率高,诊断困难。患者免疫功能差,合并症多,经过抗结核、抗病毒等治疗后大部分患者有明显好转。Objective To investigate the clinic characteristic,dlagnosis and treatment of HIV infection/AiDS combinated with mycobacterial pulmonary disease on divarication bacilli. Methods To analyse the clinic data of 133 cases HIV infection / AIDS combinated with mycobacterial pulmonary disease on divarication bacilli during Oct. 2006 to Sept. 2007. Results Main manifestation was fever and cough, and 2/3 cases had tuberculosis, 1/3 cases had nontuberculous mycobacterial disease （NTM）. Of all the cases,78 cases had pulmonary tuberculosis,26 cases had lymph tuberculosis,30 cases had two and more parts of tuberculosis. The average CD4^＋ T lymphocyte was 55 × 10^6/L, abnormal sternum x-ray examinations were found in 93 cases of them, 17 cases had positive acid-fast bacilli smear of sputum specimen and 57 cases had positive cultivation results. The mortality was 9.8% after treatment. Conclusion High infection rate,poor immunity function and more complications were found in HIV infection/AIDS combinated with divarication bacilli. It is difficult to be diagnosed, the symptoms of most cases improved obviously after anti-tuberculosis and anti-virus treatment.

关 键 词：艾滋病 分枝杆菌 肺部疾病 

分 类 号：R512.91[医药卫生—内科学]