复方芪麝片质量标准研究  

Studies on the Quality Control of Compound Qishe Tablets

作　　者：张钰泉[1] 刘新华[1] 张宁[1] 刘梅[1] 

机构地区：[1]上海中医药大学,上海201203

出　　处：《时珍国医国药》2008年第4期977-978,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的建立该制剂的质量标准。方法采用薄层色谱法对麝香酮、胆酸进行定性研究;采用HPLC-ELSD测定黄芪甲苷含量。结果在薄层色谱中检出了人工麝香和人工牛黄;黄芪甲苷在5.175-36.225μg范围内呈良好线性关系,r=0.999 9,加样平均回收率为98.66%,RSD为1.99%。结论所建立的方法简便易行,专属性强,重现性好,可作为复方芪麝片的质量控制方法。Objective To establish a quality control for Compound Qishe tablets. Methods Moschus artifactus and Calcucus bovis artifactus were identified by TLC, and astragaloside Ⅳ in the tablets was determined by HPLC - ELSD. Results The spots in the TLC were clear and distinguished well. The linear range was within the range of 5. 175 -36. 225 μg（ r = 0. 999 9）. The average recovery was 98.66%, and the RSD was 1.99%. Conclusion This methods can be used for quality control of Compound Qishe tablets.

关 键 词：复方芪麝片 黄芪甲苷 质量标准 

分 类 号：R284.1[医药卫生—中药学]