结肠癌危险因素的病例对照研究  

A Case-control Study on Risk Factors of Colonic Cancer

作　　者：赵俊仕[1] 黄民主[1] 吴心音[1] 贺小卫[1] 

机构地区：[1]中南大学公共卫生学院流行病与卫生统计学系,长沙410078

出　　处：《肿瘤防治研究》2008年第7期524-526,共3页Cancer Research on Prevention and Treatment

基　　金：湖南省计划生育委员会重点资助项目(2002-04)

摘　　要：目的探索结肠癌发病危险因素,为结肠癌防治提供科学依据。方法采用1∶1配对病例-对照研究方法,在中南大学三所附属医院选择病例和对照,按照性别和年龄配对,应用条件logistic回归对研究变量进行分析。结果多因素分析结果显示常处于坐位状态、食用油以动物油为主、胆囊疾病史、阑尾炎史以及一级亲属癌症史等为结肠癌危险因素,常吃蔬菜为结肠癌的保护因素。结论结肠癌发病受生活饮食习惯、消化系统疾病史和家族癌症史的影响。Objective To discovery the major risk factors of colonic cancer and provide some reference for proper interventions of colonic cancer. Methods A case-control study including cases and controls , who were matched by age and gender,was carried out in the three hospitals of Central South University. Factors were analyzed using conditional logistic regression. Results As the results of multivariate regression, frequently being in sitting, animal oil is the primary part of cooking oil ,cystic diseases, appendicitis and cancer history of first degree relatives were risk factors of colonic cancer, while frequently eating vegetable were protective factors of colonic cancer. Conclusion The life style and dietary habits , digestive diseases and the positive history of cancer in relatives were the major influencing factors of colonic cancer.

关 键 词：结肠癌 危险因素 病例对照研究 多因素分析 

分 类 号：R181.32[医药卫生—流行病学] R735.35[医药卫生—公共卫生与预防医学]