胰十二指肠切除术后早期呼吸系统并发症的危险因素分析  

Analysis of risk factors of early postoperative pulmonary complications after pancreaticoduodenectomy

作　　者：杨峰[1] 傅德良[1] 龙江[1] 徐近[1] 虞先浚[1] 金忱[1] 倪泉兴[1] 张延龄[1] 

机构地区：[1]复旦大学胰腺病研究所,复旦大学上海医学院附属华山医院普外科,上海200040

出　　处：《中华肝胆外科杂志》2008年第7期460-463,共4页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的 探讨胰十二指肠切除术病人术后早期呼吸系统并发症（pulmonary complications，PC）的危险因素。方法 回顾性分析165例胰十二指肠切除术病人的临床资料，采用单因素和多因素Logistic回归分析筛选与发生术后PC相关的危险因素。结果 165例病人有32例（19．4％）术后发生PC。多因素Logistic回归分析筛选出与PC有关的危险因素为：手术方式（OR=2．859）、血管重建（OR=4．803）、术后抑酸剂使用时间（OR=1．063）、术后气管插管时间（OR=1．087）。得出Logistic回归预测方程为：P（1）=1/[1＋e^-（-4.987＋1.05X1＋1.569X2＋0.061X3＋0.083X4]。结论 PPPD、联合血管重建、术后使用抑酸剂和气管插管时间长的胰十二指肠切除术病人，易发生PC。Objective To investigate the risk factors of early postoperative pulmonary complications （EPPPC） after pancreaticoduodenectomy. Methods The clinical data of 165 patients receiving pancreaticoduodenectomy in our hospital were retrospectively analyzed. The univariate and muhivari ate logistic regression analyses were used to screen risk factors of EPPPC. Results The overall inci dence of EPPPC was 19.4% （32/165）. The multivariate logistic regression analysis showed that the type of surgery （OR = 2. 859）, vascular reconstruction （OR = 4. 803）, length of postoperative antacid （OR=1. 063） and length of postoperative intratracheal intubation （OR= 1. 087） were the risk factors of EPPPC. The logistic regression equation for predicting the risk of EPPPC was P（1）=1/[1 ＋ e^-（-4,987＋1.051X1＋1.369X2＋0. 061X3＋0.083X4）]. Conclusion Patients receiving PPPD, vascular reconstruction, long-term antacid and intratracheal intubation after pancreaticoduodenectomy are apt to develop EPPPC.

关 键 词：手术后并发症 胰十二指肠切除术 呼吸系统 肺 危险因素 

分 类 号：R686[医药卫生—骨科学]