耐甲氧西林表皮葡萄球菌发生率及耐药性检测  

Detection of MRSE and resistance in staphylococcus epidermidis isolates

作　　者：刘旻[1] 熊自忠[1] 曹鸿霞[1] 

机构地区：[1]安徽医科大学第一附属医院感染病科,安徽省合肥230022

出　　处：《中国基层医药》2008年第5期708-709,共2页Chinese Journal of Primary Medicine and Pharmacy

基　　金：安徽省自然科学基金资助项目（050430804）

摘　　要：目的了解临床分离表皮葡萄球菌中耐甲氧西林菌株（MRSE）发生率及其耐药情况。方法对128株表皮葡萄球菌进行头孢西丁纸片扩散法检测耐甲氧西林株，琼脂稀释法进行药敏试验。结果128株表皮葡萄球菌中，MRSE检出率为79．7％。MRSE对多种抗菌药物耐药，对万古霉素、替考拉宁敏感，耐药率为0；除青霉素类、大环内酯类和糖肽类以外，MRSE对其他抗菌药物的耐药率均高于甲氧西林敏感表皮葡萄球菌（MSSE）。结论MRSE发生率高，耐多药，未发现糖肽类耐药株。Objective To detect MRSE and resistance in staphylococcus epidermidis isolates. Methods MRSE isolates were detected by cefoxitin disk test and susceptibilities were tested by agar dilution method. Results 79.7 % of 128 isolates were MRSE strains with resistance to most antimicrobial agents, but those isolates were still susceptible to vancomycin and teicoplanin. Resistant rate in MRSE was higher than that in MSSE to most antimicrobial agents except penicillins, glycopeptides and macrolides. Conclusion MRSE with muhi-resistance are highly prevalent in staphylococcus epidermidis isolates and no isolate is resistant to glycopeptides.

关 键 词：甲氧西林抗药性 葡萄球菌 表皮 集落计数 微生物 

分 类 号：R446[医药卫生—诊断学]