沙美特罗替卡松干粉剂吸入治疗儿童哮喘115例疗效观察  

Effect observation of 115 children with asthma treated with salmeterol/flutieasone propionate inhalation

作　　者：葛秋生[1] 陈金玉[1] 徐颂周[1] 林玉娟[1] 

机构地区：[1]北京大学深圳医院儿科 ,广东省深圳518036

出　　处：《中国基层医药》2008年第5期732-733,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的观察沙美特罗替卡松（SM／FP）干粉剂吸入治疗儿童哮喘的疗效。方法根据患儿治疗前哮喘的严重程度给予不同剂量SM／FP吸入，应用该药治疗180d以上，评价7d、30d、180d的疗效。结果经过SM／FP180d吸入治疗，显著提高了哮喘息儿的晨间最大呼气流速值、夜间最大呼气流速值，明显改善了患儿的肺功能；亦显示SM／FP能够改善患儿日夜间哮喘症状评分，减缓哮喘症状，可减少短效β2受体激动剂的使用。同时证实．在治疗第1周上述疗效指标即有显著的改善，且在治疗半年后得到持续改善。结论沙美特罗替卡松干粉剂吸入治疗小儿哮喘效果显著，值得推广应用。Objective To observe the effect of salmeterol/flutieasone propionate on children with asthma. Methods Salmeterol/flutieasone propionate inhalation of different dosages were given according to different illness condition of asthma. Investigate the effects of 180 days inhalation of SM/FP among children. Results After 180 days＇ treatment, the PEFam and PEFpm of those children of asthma were significantly increased. The lung function has a perceptible improvement. In addition, the daytime and noctural symptom scores and asthma symptom were improved. Moreover, the shote-acting 132 agonist was used with decreasing frequency. The effects of SM/FP inhalation were marvelous after 1 week of treatment and should make a long persisting time after six months of treatment. Conclusion SM/FP is an effective medicine for children with asthma and should be make more widespread.

关 键 词：哮喘 抗哮喘药 糖皮质激素 肾上腺素能Β激动剂 儿童 

分 类 号：R72[医药卫生—儿科]