雾化吸入鱼腥草提取液对大鼠呼吸道及全身免疫功能的影响  

EFFECTS OF AEROSOL INHALATION OF HOUTTUYNIA CORDATA THUNB EXTRACT ON THE IMMUNOLOGICAL FUNCTIONS IN RATS

作　　者：宁耀瑜[1] 柯美珍[1] 周晓玲[1] 杨志平[1] 宋志军[1] 

机构地区：[1]广西医科大学病理生理学教研室

出　　处：《广西医科大学学报》1997年第4期70-74,共5页Journal of Guangxi Medical University

摘　　要：为探讨雾化吸入鱼腥草提取液对大鼠免疫功能的影响。将２０只大鼠随机分为实验组和对照组，实验组雾化吸入鱼腥草提取液，而对照组则吸入雾化生理盐水。１４ｄ后处死动物，观察免疫指标，结果实验组动物肺泡巨噬细胞吞噬率，肺冲洗液中ＡＮＡＥ阳性细胞的比例和外周血ＡＮＡＥ阳性细胞的比例显著提高（Ｐ＜０．００１，Ｐ＜０．０１），对外周血白细胞移行指数具有明显降低作用（Ｐ＜０．０５）。提示雾化吸入鱼腥草提取液可显著增强呼吸道局部的特异性和非特异性免疫功能，对全身性免疫功能也有一定的促进作用。This investigation is to observe the effects of houttuynia extract aerosol inhalation on the immunological functions in rats20 rats were randomly divided into experimental group which received houttuynia aerosol inhalation,and control group which recewed normal saline inhalationAfter 14 day inhalation,the immunological function of these two groups were determinedResults:aerosol inhalation of houttuynia extract can:①increases significartly the phagocytic rate of the alvcolar macrophages(P<0001);②enhanus significantly the rate of ANAE positive cells of the peripheral blood(P<001) and lung lavage fluid(P<001);and ③decreases significantly the MIF index of the peripheral blood(P<005)This investigation indicates that aerosol inhalation of houttuynia extract not only promotes the pulmonary immunological functions,but also enhances the systemic immunological functions

关 键 词：鱼腥草 吸入疗法 免疫调节 呼吸道感染 中药 

分 类 号：R259.6[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]