田基黄体内抗甲3型流感病毒作用研究  

Effect of Anti-influenza Virus H3N2 of Hypericum japonicum in vivo

作　　者：刘妮[1] 胡溪柳[1] 孟以蓉[1] 朱宇同[1] 黄碧松[1] 林培政[1] 

机构地区：[1]广州中医药大学热带医学研究所,广东广州510405

出　　处：《中药材》2008年第7期1022-1024,共3页Journal of Chinese Medicinal Materials

基　　金：国家自然科学基金广东省政府联合基金资助项目(U0632009)

摘　　要：目的:从体内抗病毒实验观察田基黄抗甲3型流感病毒作用。方法:以病毒滴鼻感染小鼠,观察田基黄对肺指数、病毒致小鼠死亡率的影响。结果:口服10 g/kg.d田基黄可明显抑制甲3型流感病毒引起的小鼠肺组织炎性实变,降低甲3型流感病毒感染小鼠的死亡率。结论:田基黄是一种治疗流行性感冒的有效药物。Objective：To investigate anti-influenza virus H3N2 effect of Hypericum japonicum in vivo.Methods：The influences on lung index and death rate were observed in the mice infected with virus H3N2 from intranasal.Results：Experiments in vivo showed that Hypericum japonicum at the concentration of 10 g/kg·d for the intranasal treatment markedly inhibited the lung consolidation of mice pneumonia caused by the infection of influenza virus H3N2 and prolonged the survival time.Conclusion：Hypericum japonicum may be effective on treating influenza.

关 键 词：田基黄 流感病毒 

分 类 号：R285.5[医药卫生—中药学]