盐酸催化薯蓣皂苷水解过程的优化研究  

Study on Optimization of the Hydrolysis Process of Dioscin Catalyzed by Hydrochloric Acid

作　　者：李谦[1] 高向涛[1] 赵文垒[1] 刘绣华[1] 

机构地区：[1]河南大学精细化学与工程研究所,河南开封475001

出　　处：《中药材》2008年第7期1059-1062,共4页Journal of Chinese Medicinal Materials

基　　金：河南省科技厅资助项目(0511020200;0624270019);河南省教育厅资助项目(2007530001);传热强化与过程节能教育部重点实验室开放基金(KF0609)

摘　　要：目的:研究盐酸催化黄姜提取液中薯蓣皂苷水解过程的优化。方法:通过正交试验、单因素试验研究了盐酸浓度、反应温度、反应时间等因素及其交互作用对薯蓣皂苷水解的影响。结果:获得黄姜提取液的最佳水解条件为反应温度90℃,反应时间3h,盐酸浓度2.0mol/L。结论:盐酸浓度和反应温度对结果有显著影响,应着重加以控制。To study the optimization of hydrolysis process of dioscin catalyzed by hydrochloric acid.Methods：The effects of hydrochloric acid concentration,reaction temperature,reaction time and their interactions had been investigated using orthogonal design and single-factor experiments.Results：The optimum hydrolysis conditions were as follows：reaction temperature 90℃,reaction time 3h,hydrochloric acid concentration 2.0mol/L.Conclusion：Hydrochloric acid concentration and reaction temperature should be controlled because of their remarkable influence on hydrolysis process.

关 键 词：薯蓣皂苷 正交设计 水解 薯蓣皂苷元 

分 类 号：R286.02[医药卫生—中药学]