海南狗牙花化学成分  

Chemical Constituents from the Roots and Stems of Ervatamia hainanensis

作　　者：金丽[1] 卢嘉[1] 金永生[1] 杨向楠[1] 陈海生[1] 

机构地区：[1]第二军医大学药学院天然药物化学教研室

出　　处：《中国天然药物》2008年第4期271-274,共4页

基　　金：国家自然科学基金(No.20272081);上海市重点学科建设项目资助(No.B906)~~

摘　　要：目的:研究海南狗牙花的化学成分。方法:采用多种柱层析方法分离和纯化化合物,用光谱方法确定化合物的结构。结果:分离得到10个化合物,其化学结构鉴定为:8-羟基-6-甲氧基-3-正戊基异香豆素(1),环阿尔廷醇(2),23-环木菠萝烯-3β,25-二醇(3),钝叶甾醇(4),α-香树脂醇(5),α-香树脂醇乙酸酯(6),11-氧代-α-香树脂醇乙酸酯(7),β-香树脂醇乙酸酯(8),豆甾醇(9),[24S]-豆甾-4-烯-3-酮(10)。结论:化合物1,4,9和10为首次从该植物中分得。化合物1和4为首次在该属植物中发现。AIM： To study the chemical constituents of Ervatamia hainanensis. METHODS： Chemical constituents were isolated by various column chromatographic techniques and their structures were elucidated by spectroscopic methods. RESULTS： Ten compounds were obtained from Ervatamia hainanensis and identified as 8-hydroxy-6-methoxy-3- n-pentylisocoumarin （1）, cycloartenol, （2） cycloart-23-ene-3β, 25-diol （3）, obtusifoliol （4）, α-amyrin （5）, α-amyrin acetate （6）, 11-oxo-cz-amyrin acetate （7）, β-amyrin acetate （8）, stigmasterol （9）, stigmasta-4-en-3-one （10）, respectively. CONCLUSION： Compounds 1, 4, 9 and 10 have been isolated from this plant for the first time, and compounds 1 and 4 have been first obtained from Ervatamia genus.

关 键 词：海南狗牙花 香豆素类 三萜类 

分 类 号：R284.1[医药卫生—中药学]