半导体激光血管内照射对人体外周血T淋巴细胞亚群及NK细胞的调节作用  

The effects of Diode Laser ILIB on Peripheral Blood T Lymphocytes Subpopulations and NK cells

作　　者：徐清[1] 史桂英[1] 许松林[1] 成柏华[2] 王如瑶[2] 朱雅芬 俞庆宪 吴之畏 

机构地区：[1]上海第二医科大学生物物理教研室 [2]上海第二医科大学神经生物学实验室 [3]上海东南医院

出　　处：《激光生物学报》1997年第3期1105-1109,共5页Acta Laser Biology Sinica

基　　金：国家自然科学基金

摘　　要：本文报道了半导体激光血管内照射对人体外周血Ｔ淋巴细胞亚群及ＮＫ细胞的免疫调节作用。实验结果提示：在２３例经６５０ｎｍ．５ｍＷ的半导体激光血管内照射治疗一次，五次和十次的患者中，ＣＤ＋３细胞亚群的百分比与照射前（６３．６６％）比较，分别提高到６５．８６％，６９．９４％，７５．０４％。ＣＤ＋４Ｔ辅助细胞在第十次治疗后也有所增加。除此之外，半导体激光血管内照射对ＮＫ细胞比例及ＣＤ＋４／ＣＤ＋８比值具有双向调控作用，即偏离（即高于或低于）正常值的患者经照射后恢复到正常水平。这种双向调控作用将对临床治疗更有指导意义。The immuno-regulation effect of diode laser ILIB on T lymphocytes subpopulations and NK cells has been studied. The results showed that there were an improving effect on the CD +3,CD +4,CD +8,and NK cells after a period of diode laser (650nm,5mW,CW) ILIB in 23 patients.The mean value of CD +3% was inceased on the lst ,5th and 10th times ILIB separately (65 86%,69 94%,75 04%) compared with the data (63 66%) before treatment.The mean value of CD +4% only increased on the 10th treatment. In spite of the CD +8 was a increased tendency and the mean value of NK % was increased on the lst time of ILIB (23 66 to 26 90%) but a modulating effect had been seen, which modulated the abnormal levels of NK cell and CD +4/CD +8 to the normal levels,so it would be a more useful effect clinically.

关 键 词：半导体激光 血管内照射 T淋巴细胞 激光疗法 

分 类 号：R454.2[医药卫生—治疗学]