蒙药蒙古锦鸡儿的质量标准研究  

Studay on quality standard of mogolian medicine materia Caragana sibirica

作　　者：杨九艳[1] 邵红霞[2] 韩继新[2] 格日乐[2] 李海霞[2] 邱君[2] 

机构地区：[1]内蒙古大学生命科学学院,内蒙古呼和浩特010021 [2]内蒙古医学院药学院,内蒙古呼和浩特010059

出　　处：《中国医院药学杂志》2008年第14期1148-1151,共4页Chinese Journal of Hospital Pharmacy

基　　金：内蒙古自治区蒙药现代化重大科技专项资助项目(编号:MX2005ZB011);内蒙古大学高层次引进人才科研启动基金资助项目

摘　　要：目的:制定蒙药蒙古锦鸡儿质量标准,为该药材资源的开发利用提供科学依据。方法:对5个不同产地的蒙药蒙古锦鸡儿进行性状及显微特征鉴别;用薄层层析法以β-谷甾醇为对照品进行鉴别;用水分测定法、灰分测定法、浸出物测定法进行相应的检查;采用高效液相色谱法以芦丁为对照品进行定量研究。结果:5个不同产地的蒙古锦鸡儿在与对照品色谱相应的位置上,显相同颜色的荧光斑点;水分含量均在8.31%以下,总灰分均在10.68%以下,酸不溶性灰分均在1.37%以下,醇溶性浸出物含量均在16.0%以上;芦丁的含量均在0.08%以上。结论:通过研究制定了蒙古锦鸡儿的质量控制标准。OBJECTIVE To provide scientific basis for the utilization and development of Caragana sibirica by setting up the quality control criteria of C. sibirica. METHODS Characteristics and micro-features of 5 Mogolian medicinl materia Caragana sibirica samples from different habitats were observed. The samples were identified by TLC with β-sitosterol as reference. Moisture ash and extractives were determined HPLC was used for assay with rutin as a reference substance. RESULTS The 5 Caragana sibirica from different habitats presented the spots of the same colors with the control chromatogram at the corresponding position. The water content was below 8. 31%, the average content of ash was less than 10. 68% and acid insoluble ash was under 1.37%. Ethanol soluble extractives were above 16. 0% and rutin content was more than 0. 08%. CONCLUSION The methods developed in this experiment can be used for the quality control of C. sibirica.

关 键 词：蒙古锦鸡儿 质量标准 薄层色谱法 高效液相色谱法 

分 类 号：R282.5[医药卫生—中药学]