Efficient Synthesis of 3,5,6,7-Tetrahydro-4H-cyclopenta [4,5] thieno [2,3-d] Pyrimidin-4-ones  

作　　者：LIU Ming-guo ZHONG Ying DING Ming-wu 

机构地区：[1]Key Laboratory of Pesticide ＆ Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, P. R. China [2]Hubei Key Laboratory of Natural Products Research and Development, China Three Gorges University, Yichang 443002, P. R. China

出　　处：《Chemical Research in Chinese Universities》2008年第4期437-440,共4页高等学校化学研究（英文版）

基　　金：the National Natural Science Foundation of China(No.20772041);the Opening Foundation of the Key Labo-ratory of Three Gorges University of China(No.2006NP01);the Key Project of Chinese Ministry of Education(No.107082)

摘　　要：The title compounds 3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ones（6） were synthesized by base catalytic reactions of secondary amines with carbodiimides 4, which were obtained from the aza-Wittig reaction of iminophosphoranes（3） with aromatic isocyanates.The title compounds 3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ones（6） were synthesized by base catalytic reactions of secondary amines with carbodiimides 4, which were obtained from the aza-Wittig reaction of iminophosphoranes（3） with aromatic isocyanates.

关 键 词：Cyclopenta[4 5]thieno[2 3-d]pyrimidin-4-one Aza-Wittig reaction CARBODIIMIDE ISOCYANATE 

分 类 号：O625[理学—有机化学]