中药复方治疗痛经用药规律  

Laws of compound traditional Chinese medicine in treatment of dysmenorrhea

作　　者：倪建俐[1] 张攀[2] 任福尧[2] 

机构地区：[1]上海交通大学医学院新华医院中医科,上海200092 [2]复旦大学数学系,上海200433

出　　处：《中西医结合学报》2008年第8期783-787,共5页Journal of Chinese Integrative Medicine

摘　　要：收集近20年来治疗痛经的中药复方176首,建立中药复方数据库,用频率分析法分析药物的使用比例、使用频率和剂量;用单指标和多指标的多因子线性逐步回归统计学方法,筛选决定单指标和多指标的主要药物,建立回归方程,预测复方的临床疗效。得出在173种中药中,活血化瘀类中药和理气类中药的使用比例和使用频率最高;统计出常用的20味中药的剂量区间;建立单指标和多指标的线性逐步回归方程,筛选出决定单指标和多指标中各指标的主要药物,并用单指标回归方程检验了176首处方的总有效率,其绝对误差在4%以内的有167首,占总处方的94.89%。提示活血理气类药物为最常用的药物;建立的逐步回归方程能较为精确地预测复方治疗痛经的临床疗效。Compound traditional Chinese medicine database was established by collecting 176 compound formulas for dysmenorrhea in the last twenty years.The proportion and frequency of herbal medicine were analyzed and the main herbs with mono-target or multi-target in the compound formulas were selected with simple and multiple linear regression.The linear regression equations were listed and the clinical effects of the compound formulas were evaluated.Of 173 herbs used in the compound formulas,the proportion and frequency of the herbs for activating blood and transforming stasis and regulating qi flow were high in the application.The dosage interval for 20 herbs in common use was estimated.Main herbs with mono-target or multi-target used in the compound formulas were selected with simple and multiple linear regression.The total effectiveness rate of the 176 compound formulas was tested with simple linear regression,and 167 compound formulas（94.84 % of the total） had the Absolute error less than 4%.Herbs for activating blood and transforming stasis and regulating qi flow are most commonly used in treatment of dysmenorrhea.Clinical effects of the compound formulas could be forecast with stepwise regression equation.

关 键 词：痛经 中药 复方 回归分析 

分 类 号：R271.113[医药卫生—中医妇科学]