腹腔镜下切取活体供肝技术的实验研究  

Laparoscopic living donor hepatectomy for liver transplantation in porcine

作　　者：王成友[1] 张敏杰[1] 梁浩辉[1] 倪勇[1] 詹勇强[1] 廖允军[1] 

机构地区：[1]深圳市第二人民医院肝胆外科,518035

出　　处：《安徽医学》2008年第5期516-518,共3页Anhui Medical Journal

基　　金：广东省医学基金资助课题(A2005625)

摘　　要：目的探讨腹腔镜活体供肝切取的技术及可行性。方法运用腹腔镜系统对猪（n=3）进行左肝切取，操作参照人活体肝移植供体要求进行，观察手术过程中供体生命征，总腹腔镜操作时间、左肝管道系统分离时间、肝组织分离时间、供肝温缺血时间及术中出血量，并测量供肝质量参数。结果（1）手术过程中血压、呼吸、心率、血气参数稳定，均较顺利取出活体供肝，出血量较少。（2）切取的供肝左肝动脉长约1．6—1．8cm，左肝门静脉长约0．8—1．0cm，左肝管约0．6—0．8cm，左肝静脉约0．2—0．3cm。经左肝动脉及门静脉灌注良好，温缺血时间为5min；5min；4min。结论从技术层面而言，腹腔镜下猪活体取肝是可行的。Objective To study the techniques and feasibility of laparoscopic living donor hepatectomy. Methods Three pigs were studied and laparoscopic left hepatic lobectomy performed. The procedure was conferred to human. The vital signs were monitered. Time of operation, dissection of left heptic blood vessels and heptic duct, dissection of liver parenchyma, and warm ischemia was recorded. Blood loss and the left liver were measured. Results The vital signs were stable and safe, and the operations were performed successfully with a blood loss of 200ml. 2. The lengths of left hepatic artery were 1.6cm - 1. 8cm, left portal vein 0.8 -1.0cm, hepatic duct 0.6 - 0.8cm, hepatic vein 0.2 -0.3cm, and the perfusion of left livers was satisfied. The warm ischemia times were 5min ; 5min; 4rain. Conclusion The porcine laparoscopic living donor hepatectomy was feasible from a technical perspective.

关 键 词：活体肝移植 腹腔镜术 微创术 供体 猪 

分 类 号：R657.3[医药卫生—外科学] R657.4[医药卫生—临床医学]