氯麻滴鼻液处方的改进及临床验证  

Formula Improving of Chloramphenicol and Ephedrine Nasal Drops

作　　者：常效春[1] 潘西芬[1] 王书丽[1] 

机构地区：[1]山东聊城市第二人民医院,临清市252601

出　　处：《中国药房》2008年第23期1805-1806,共2页China Pharmacy

摘　　要：目的:对《中国医院制剂规范》氯麻滴鼻液处方中甘油的用量作进一步探讨和改进。方法:通过处方筛选比较和临床试验观察,将原处方中的甘油用量由300mL减为50mL。结果与结论:改进后的处方甘油量所配氯麻滴鼻液,刺激性大大减小,透明度也好,患者易接受,成本降低,值得推广应用。OBJECTIVE： To optimize the ratio of glycerol in Chloramphenicol and Ephedrine Nasal Drops included in China＇s Hospitals Agents Norms. METHODS： By formula optimization and observation on clinical trials, the ratio of glycerol in Chloramphenicol and Ephedrine Nasal Drops was reduced from 300mL to 50mL. RESULTS ＆ CONCLUSION： The Chloramphenicol and Ephedrine Nose Drops prepared in an optimized ratio of glycerol is of much less irritability, good transparency, good compliance in patients, more reliable efficacy, thus deserving to be popularized.

关 键 词：氯麻滴鼻液 甘油 渗透压 临床观察 

分 类 号：R987[医药卫生—药品] R289.1[医药卫生—药学]