珠海地区246例药品不良事件报告分析  

Adverse Drug Events in Zhuhai Area:Analysis of 246 Cases

作　　者：周轶[1] 陈卫果[1] 

机构地区：[1]广东珠海市人民医院,珠海市519000

出　　处：《中国药房》2008年第23期1816-1817,共2页China Pharmacy

摘　　要：目的:了解珠海地区药品不良事件的发生情况、特征及影响因素。方法:收集2007年1～9月该地区上报的246例药品不良事件,并作统计分析。结果:246例药品不良事件中,涉及品种最多为抗感染药(43.24%),与其品种繁多、使用频率高、应用范围广有关;发生药品不良事件的主要给药途径为静脉给药(78.05%);药品不良事件最常累及皮肤及其附件(41.12%);119例(48.37%)存在不按说明书用药,其中113例涉及抗感染药。结论:医务工作者应加强药物知识的学习,注意药物使用各环节的安全。OBJECTIVE： To investigate the incidence, clinical features and influential factor of adverse drug events appeared in Zhuhai area. METHODS： 246 cases with adverse drug events reported in our hospital from Jan. to Sep. in 2007 were analyzed statistically. RESULTS： Of the total drugs inducing adverse drug events （246 cases）, antiinfectives took the lead （43.24%）, which was related to its great variety, high application frequency and application range; 78.05% were induced by intravenous infusion; 41.12% were manifested as lesion of skin and its appendants; 119 （48.37%） failed to follow the direction of package inserts, of which, 113 cases involved the use of anti infectives. CONCLUSION： Medical workers should attach great importance to the acquisition of medication knowledge as well as the medication safety at each steps.

关 键 词：药品不良事件 监测 统计分析 

分 类 号：R969.3[医药卫生—药理学] R95[医药卫生—药学]