高胆血红素血症新生儿换血治疗前后红细胞免疫功能的变化  

The immunological functionl change of red blood cells in hyperbilirubinemia neonate before and after exchange transfusion treatment

作　　者：张修发[1] 江凡[1] 祝爱霞[1] 邹建话[1] 

机构地区：[1]广东省深圳市宝安区妇幼保健院,518133

出　　处：《中国妇幼保健》2008年第23期3258-3260,共3页Maternal and Child Health Care of China

基　　金：深圳市科技局自然科技资金资助(项目编号:JH200505310573A)

摘　　要：目的:探讨高胆新生儿换血治疗前后红细胞功能的变化,为高胆新生儿合理有效治疗提供依据。方法:采用祝爱霞红细胞免疫功能测量微量法。结果:换血前后红细胞未洗涤RBC-C3bRR、RBC-ICR比较,P<0.001。差异非常显著;换血前红细胞洗涤与未洗涤RBC-C3bRR、RBC-ICR比较,P<0.001,差异非常显著;换血后红细胞洗涤与未洗涤RBC-C3bRR比较,P>0.05,差异无显著意义,RBC-ICR比较,P<0.001,差异非常显著。结论:高胆血红素血症新生儿换血治疗可以增强新生儿红细胞免疫功能,提高新生儿抗感染能力。Objective： To expolre the immunological funetionl change of red blood cells in hyperbilirubinemia neonate before and after exchange transfusion treatment and provide reasonable and effective treatment. Methods： Zhuaixia red blood cell immunoreagent and micromethod was uesd to measure the immunological functionl of red blood ceils. Results： There was obviously difference between before and after exchange transfusion treatment in unwashed RBC - C3bRR and RBC - ICR （ P 〈 0. 001 ） . There was obviously difference between washed and unwashed RBC -C3bRR and RBC -ICR before exchange transfusion treatment （P 〈0. 001 ） . There wasnt difference between washed and unwashed RBC - C3bRR after exchange transfusion treatment （ P 〉 0. 05 ） , while there was obviously difference between washed and unwashed RBC -ICR after exchange transfusion treatment （P 〈 0. 001 ） . Conclusion： Exchange transfusion treatment may strengthen the immunological functionl of red blood cells in hyperbilirubinemia neonate and increase their anti - infection ability.

关 键 词：RBC—C3bRR RBC—ICR高胆血红素血症 新生儿 换血治疗 

分 类 号：R722.17[医药卫生—儿科]