动物肝脂肪变性的分子机制  

Molecular Mechanism of Hepatic Steatosis in Animal

作　　者：韩春春[1] 王继文[1] 

机构地区：[1]四川农业大学动物科技学院,四川雅安625014

出　　处：《中国畜牧杂志》2008年第15期53-55,共3页Chinese Journal of Animal Science

基　　金：四川省十一五育种攻关项目(2006YZGG-20);四川省教育厅重点专项(2004D001)

摘　　要：肝脏中脂肪酸代谢平衡的破坏是肝脂肪变性的主要原因,胰岛素和葡萄糖都能独立调控肝脏中脂肪酸的生成,在这些调控中起重要作用的转录因子如SR EBP-1,C hR EBP,PPAR等与肝脂肪变性的发生有紧密联系。The disbalance of fatty acids metabolic in liver is the main reason of hepatic steatosis. De novo synthesis of fatty acids in liver is regulated independently by insulin and glucose, and some transcription factors which have important roles in the regulation such as SREBP- 1,ChREBP, PPAR have close connection with hepatic steatosis.

关 键 词：肝脂肪变性 胰岛素 葡萄糖 转录因子 

分 类 号：S834.1[农业科学—畜牧学] S835.1[农业科学—畜牧兽医]