益视颗粒的质量标准研究  

Study on quality control of Yishi Granules

作　　者：冯乙巳[1,2] 胡来月[1] 朱玉川[1] 吴宜南[1] 张宵翔[1] 孙松 

机构地区：[1]合肥工业大学化工学院,安徽合肥230009 [2]农产品生物化工工程研究中心,安徽合肥230009 [3]合肥远志医药科技开发有限公司,安徽合肥230031

出　　处：《药物分析杂志》2008年第7期1166-1169,共4页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立益视颗粒的质量标准。方法:用 TLC 法对益视颗粒进行定性鉴别;并用 HPLC 法测定益视颗粒中有效成分的含量.结果:薄层色谱法可鉴别方中制何首乌、厚朴、木香的对应斑点;HPLC 法可测定有效成分2,3,5,4′-四羟基二苯乙烯-2-O-B-D-葡萄糖苷的含量。结论:本法操作简便,重现性好,结果准确,可作为该制剂的质量控制方法。Objective：To establish the quality standard of Yishi Granules. Methods：Yishi Granules was identified by TLC;the effective components of Yishi Granules was determined by HPLC. Results：The relevant spots in Radix polygoni multiflori preparata, Cortex magnoliae officinalis and Radix Aucklandiae were identified by TLC;The conents of 2,3,5,4′ - Tetrahy - droxystilbene - 2 - O - β - D - glueoside be etermined by HPLC. Conclusion： The method was simple with specificity and good reproducibility and could be used for quality control for Yishi GranuLes.

关 键 词：益视颗粒 四羟基二苯乙烯苷 制何首乌 TLC HPLC 

分 类 号：R917[医药卫生—药物分析学]