多功能材料实验机在透皮贴剂黏附力测定中的应用  

Application of multifunction material tester for adhesive power testing of transdermal drug deliver systems

作　　者：陈华[1] 汤龙[1] 左宁[1] 

机构地区：[1]中国药品生物制品检定所,北京100050

出　　处：《药物分析杂志》2008年第7期1214-1216,共3页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:找出一种适用于透皮贴剂黏附力测定的实验方法。方法:利用多功能材料实验机记录拉力-距离曲线,利用曲线下面积计算Ⅲ平均拉力。结果:用于多种进口透皮贴剂黏附力的测定,控制了其产品质量。结论:本方法方便、可靠,适于对产品的质量进行有效控制。Objective ：To find out a method for adhesive testing of transdermal drug deliver systems （TDDS）. Method：Recording the curve of force-distance by multifunction tester, and calculating the average force with AUC. Result：Tested the adhesive power of some kinks of TDDS, and controlled the quality of products. Conclusion：The method is convenient and reliable. It is suitable for the effective control of quality.

关 键 词：透皮贴剂 黏附力 剥离强度 

分 类 号：R917[医药卫生—药物分析学]