2006年盐城市盐都区部分2～10岁儿童乙型肝炎病毒感染状况调查  

Infection Investigation on HBV among the Children Aged from 2 to 10 in Yandu District of Yancheng City in 2006

作　　者：许红[1] 王荣堂[2] 

机构地区：[1]江苏省盐城卫生职业技术学院,江苏盐城224006 [2]江苏省盐城市盐都区疾病预防控制中心,江苏盐城224002

出　　处：《预防医学论坛》2008年第9期791-792,共2页Preventive Medicine Tribune

摘　　要：[目的]了解2～10岁儿童乙型肝炎病毒（HBV）感染状况、感染原因及将乙肝疫苗纳入计划免疫管理后的效果。[方法]2006年4～6月,对盐城市盐都区4个乡镇1646名2～10岁儿童进行HBV感染情况血清学调查，并对乙肝病毒表面抗原（HBsAg）阳性儿童检测与其父母的DNA同源性。[结果]调查1646名儿童．HBsAg阳性率为0．67％，乙肝病毒表面抗体（抗-HBs）阳性率为72．66％．乙肝病毒核心抗体（抗-HBc）阳性率为2．19％。抗-HBs阳性率．2～10岁为69．68％～75．41％（P〉0．05）。11名HBsAg阳性儿童中，8名接种过乙肝疫苗，DNA序列同源性分析，7名感染来自母亲．1名感染来自父亲。[结论]盐都区2～10岁儿童HBV感染率较低，保护性抗体各年龄段均无下降趋势；HBsAg阳性儿童的感染多来源于垂直感染。[Objective]To explore the infection situation of HBV among the children aged from 2 to 10 in Yandu District, Yancheng City, find out the causes of infection and the effect after it was brought into EPI program. [Methods]Serum samples collected from 1 646 children aged from 2 to 10 of 4 towns were tested for HBV infection＇in Yandu District. Yancheng City from April to June,2006. DNA homology between HBV-infected children and their parents was analyzed. [Results]Of the 1 646 children,the positive rate of HBsAg was 0. 67%,the positive rate of anti-HBs was 72.66 %,while the positive rate of anti-HBc was 2.19%. Among the children aged from 2 to 10, the positive rate of anti-HBC was 69.68% to 75.41%（ P〉0. 05）. Of the 11 HBsAg positive children,8 have been vaccinated. And about the analysis of DNA sequence homology, seven infections are from mother,one is from father. [Conclusion] Among these children aged from 2 to 10,the rate of HBV infection is much low,there was no declined tendency about the protective anti-HBs in all age group. Most infections of the kids with positive HBsAg came from vertical infection.

关 键 词：儿童 乙型肝炎病毒 血清标志物 感染 

分 类 号：R512.62[医药卫生—内科学]