122例卵巢早衰患者中医证候分析及致病因素调查  

Syndrome Analysis and Etiological Factor Survey of 122 Patients with Premature Ovarian Failure

作　　者：滕秀香[1] 

机构地区：[1]首都医科大学附属北京中医医院,北京100010

出　　处：《中国中医药信息杂志》2008年第4期18-20,共3页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的探讨卵巢早衰中医证候及分布规律、卵巢早衰发病原因与中医证候的关系。方法对122例卵巢早衰患者进行病情、病因调查及中医辨证。结果卵巢早衰中医症状临床呈多样趋势。122例卵巢早衰患者中,肝郁肾虚证33.61%,肝肾阴虚证18.03%,脾肾阳虚证15.57%,热盛伤津证15.57%,肾虚血瘀证8.20%,肝郁脾虚证7.38%。在68.03%卵巢早衰患者病史中可找到现代生活环境及生活方式因素对疾病发生的影响。因情致因素致病者占31.15%,因药物、疾病因素致病者占31.97%;因情志及药物、疾病双重因素致病者占4.92%。因情志因素致病组,以肝郁肾虚证比例最高(P<0.05);因药物、疾病因素致病组,以热盛伤津证、肝郁肾虚证所占比例较高(P<0.05);无诱因致病组37例,以肝肾阴虚、肝郁肾虚、脾肾阳虚三证为主,3组比较,P>0.05。结论肝郁肾虚、肝肾阴虚、脾肾阳虚、热盛伤津为卵巢早衰常见证候;除患者个体先天禀赋不足、肾气未盛、冲任气血不充或由遗传因素致卵巢早衰外,现代生活环境及生活方式因素对卵巢早衰发病有促进作用。Objective To explore the TCM syndrome and its distribution regularity of premature ovarian failure （POF） as well as the relation between the etiological factor and TCM syndrome of it. ~ The pathogenetic condition and etiological factor of 122 patients with POF were surveyed, and TCM syndrome differentiation was carried out on them. Results The TCM symptoms of POF manifested the tendency of variety. Among the 122 cases, Gan-stagnation and Shen-deficiency type accounted for 33.61% of them, Gan-Shen yin deficiency type for 18.03%, Pi-Shen yang deficiency type for 15.57%, Jin damage due to excessive heat type for 15.57%, Shen-deficiency blood stasis type for 8.20%, and Gan-stagnation and Pi-deficiency type for 7.38%. The influence of modem living environment and life style to the disease was found in 68.03% of the patients＇ case history. 31.15% of the patients was induced by emotion, 31.97% by drugs and disease, and 4.92% by both of them. In patients induced by emotion, the proportion of Gan-stagnation and Shen-deficiency type was the highest as compared with the other types （P〈0.05）. In patients induced by drugs and disease, compared with the other 4 types, Jin damage due to excessive heat type as well as Gan-stagnation and Shen-deficiency type were higher （P〈0.05）. In 37 patients without obvious etiological factor, Gan-Shen yin deficiency type, Gan-stagnation and Shen-deficiency type as well as Pi-Shen yang deficiency type were the most, but no significant difference was shown among them （P〉0.05）. Conclusion Gan-stagnation and Shen-deficiency type, Gan-Shen yin deficiency, Pi-Shen yang deficiency type and Jin damage due to excessive heat are the commonly encountered syndromes in patients with POF. Besides the congenital, Shen-Qi and Chong-Ren Qi-blood insufficiency as well as the genetic factor, the modem living environment and life style have the promotion in the genesis of POF.

关 键 词：卵巢早衰 中医证候 病因 

分 类 号：R271.917.5[医药卫生—中西医结合]