影响心内直视手术加射频消融迷宫术治疗心房颤动疗效的因素  

Factors influencing the efficacy of radiofrequency ablation Maze procedure combined with open-heart operation for treatment of atrial fibrillation

作　　者：王邵华[1] 王春生[2] 

机构地区：[1]上海交通大学附属第一人民医院胸外科,200080 [2]复旦大学附属中山医院心脏外科

出　　处：《上海医学》2008年第7期467-469,共3页Shanghai Medical Journal

摘　　要：目的分析影响心内直视手术加射频(RF)消融迷宫(Maze)术治疗心房颤动(AF)疗效的因素。方法连续收集58例接受心内直视手术加RF消融MazeⅢ术患者的临床资料并随访患者的心电图,运用COX回归分析确定影响手术疗效的独立因素。结果本组失访3例,随访率为94.8%(55/58),随访6～28个月,平均随访时间为(14.2±6.5)个月,最后1次随访中窦性心律恢复率为76.4%(42/55)。术前AF病程>4年是影响心内直视手术加RF消融Maze术治疗AF疗效的独立危险因素(P=0.025)。结论AF病程影响心内直视手术加RF消融Maze术治疗AF的疗效,AF病程越长,手术效果越差。Objective To analyze the factors influencing the efficacy of radiofrequency ablation Maze procedure combined with open-heart operation for treatment of atrial fibrillation. Methods The clinical data of 58 consecutive patients, who underwent radiofrequency modified Maze procedure combined with open-heart surgery for atrial fibrillation, were collected. The findings of most recent electrocardiogram examination were obtained through follow-up. COX＇s regression analysis was applied to identify the independent factors influencing the efficacy of radiofrequency modified maze procedure. Results Follow-up was completed in 94.8 （55/58）patients with a mean follow-up duration of （14.2±6.5） months. The latest follow-up showed that the rate of sinus rhythm restoration was 76. 4% （42/55）. Longer pre-operative duration of atrial fibrillation （〉4 years） was an independent factor influencing the efficacy of radiofrequency modified Maze procedure for atrial fibrillation（P= 0. 025）. Conclusion Pre-operative duration of atrial fibrillation can significantly influence the efficacy of radiofrequency ablation Maze procedure for patients with atrial fibrillationl The longer the duration of atrial fibrillation, the worse the efficacy of the procedure to restore sinus rhythm.

关 键 词：心房颤动 迷宫手术 射频消融 影响因素 

分 类 号：R654.2[医药卫生—外科学]