双酰基肼类昆虫生长调节剂的作用机理及抗药性研究进展  

Progress in the Study on the Action Mechanism and Insecticide Resistance of Bishydrazide Insect Growth Regulator

作　　者：贾变桃[1] 

机构地区：[1]山西农业大学农学院,山西太谷030801

出　　处：《现代农药》2008年第4期9-13,共5页MODERN AGROCHEMICALS

摘　　要：双酰基肼类杀虫剂是近几年陆续开发的一类高效、选择性强、对环境友好的昆虫生长调节剂,其作用靶标与昆虫蜕皮激素(20E)一样,结合于蜕皮激素受体(EcR)——过剩气门蛋白(USP)的异源二聚体,诱导昆虫早期基因的转录,但由于双酰肼类化合物在昆虫体内的持续存在,使20E不存在情况下发生的事件不能进行,如多巴脱羧酶(DDC)等基因的表达受阻,不合成几丁质,羽化激素不能释放,最后使幼虫早熟脱皮而死亡。随着这类杀虫剂使用时间和范围的不断扩大,对其抗药性的研究也逐渐引起了重视。本文主要综述了这类新型杀虫剂作用机理及抗药性等方面的研究进展。In recent years, Bishydrazide were developed as a new class of insect growth regular, which were highly effective and selective to the target pests and friendly to the environment. Like 20-hydroxyecdysone （20E）, Bishydrazide analogs bind to the receptor complex, a heterdimer of the ecdysone receptor （EcR） and ultraspiracle proteins （USP） and induce the transcription of the early genes. However, because of the persistence of the Bishydrazide compounds in the insect body, the events that occur in the absence of 20E do not proceed, the expression of the genes such as DOPA decarboxylase （DDC） is repressed, chitin is not synthesized, the eclosion hormone can not be released and the end results is an incomplete precocious molt, resulting in the death of the larva. With the range expansion and the time prolong of their usage, study on resistance to this class of insecticide is gradually emphasized. This paper reviewed the action mechanism and insecticide resistance of Bishydrazide insect growth regulator.

关 键 词：双酰基肼类 作用机理 抗药性 

分 类 号：S482.3[农业科学—农药学]