变应性鼻炎血清特异性IgE及皮肤点刺实验与症状的相关性  

Relationship Between Serum Specific IgE,Skin Prick Test and Symptom's Degree of Allergic Rhinitis

作　　者：师小径[1] 马艳红[1] 李亮明[1] 谭国林[1] 

机构地区：[1]中南大学湘雅三医院,湖南长沙410013

出　　处：《实用预防医学》2008年第4期1063-1064,共2页Practical Preventive Medicine

摘　　要：目的探讨变应性鼻炎血清特异性IgE(sIgE)及皮肤点刺实验与症状的关系。方法对40例变应性鼻炎患者进行症状评分,同时实施标准化皮肤点刺试验,采用UniCAP系统检测仪检测血清特异性IgE,并进行外周血嗜酸细胞(Eosinophil,Eos)计数。结果血清特异性IgE水平与皮肤点刺试验阳性强度及外周血嗜酸细胞计数具有显著的相关性(相关系数分别为0.483和0.384,P<0.05);血清特异性IgE水平和皮肤点刺试验阳性强度与变应性鼻炎的症状积分无显著相关性(P>0.05)。结论血清特异性IgE水平和标准化皮肤点刺试验阳性强度不能反应症状的程度,但任选一种方法对变应性鼻炎的诊断和鉴别诊断有重要的临床意义。Objective To explore the relationship between serum specific IgE, skin prick test and symptom＇s degree of allergic rhinitis. Methods Symptom was individually scored in 40 patients, and skin prick test was carried out using ALK standard allergen, and specific IgE was detected by UniCAP system. Peripheral blood eosinophil was counted in all patients. Results Serum specific IgE level was significantly related to positive degree of skin prick test and the concentration of peripheral blood eosinophil （r = 0. 483, r = 0. 384, P〈 0.05）. Serum specific IgE and skin prick test did not relate to score of symptom of allergic rhinitis （P 〉 0.05）. Conclusions The level of serum specific IgE and positive degree of skin prick test could not reflect symptom＇s degree in allergic rhinitis. Alternation of two assays is of great value to clinical diagnosis and differential diagnosis of allergic rhinitis.

关 键 词：变应性鼻炎 皮肤点刺试验 特异性IGE 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]