骨组织工程材料β-磷酸三钙及其复合材料改性的研究进展  

Research Progress of Modified β-TCP Materials and composites for Bone Tissue Engineering

作　　者：胡卫岚[1] 陈晓明[1] 李湘南[1] 

机构地区：[1]武汉理工大学生物材料工程研究中心,湖北武汉430070

出　　处：《生物骨科材料与临床研究》2008年第4期43-47,共5页Orthopaedic Biomechanics Materials and Clinical Study

摘　　要：β-TCP具有良好的生物相容性和骨传导性,作为生物降解材料,已被广泛应用于各种骨缺损修复。然而,β-TCP单独使用时,尚存在降解速度与骨生长不匹配、缺乏骨诱导效应等急需改进的问题。本文综述了近十年国内外关于β-TCP及其复合材料改性的研究进展,并对骨组织工程材料β-TCP未来的研究方向予以了展望。β-TCP ceramics have good biocompatibility and excellent osteoconductivity, as a kind of biodegradable substitute materials they are used widely for bone defect reparation in clinical. However, when β-TCP was prepared alone, it is not only lacking of osteoinductivity, but also the material＇s degradation process does not match bone growth rate. Research progress of modified β-TCP materials in a decade was summarized in this paper. Lastly, the research direction of β-TCP materials for bone tissue engineering was prospected.

关 键 词：Β-TCP 复合材料 改性 骨诱导性 骨缺损修复 

分 类 号：R318.08[医药卫生—生物医学工程]