杏丁联合速效救心丸对急性冠脉综合征病人纤溶活性的影响  

Influence of Xingding Injection with Suxiaojiuxinwan on Fibrinolytic Activity in Acute Coronary Syndrome

作　　者：郑泽荣 肖波 冼志莲 骆洁恒 

机构地区：[1]于广东省湛江市第二中医院 [2]广东省湛江市第二中医院

出　　处：《中西医结合心脑血管病杂志》2008年第8期900-902,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的观察杏丁注射液联合速效救心丸对急性冠脉综合征(ACS)病人纤溶活性的影响。方法ACS病人96例随机分为治疗组(杏丁注射液加速效救心丸组)和对照组(杏丁注射液组),用药前及2个疗程后检测血浆组织型纤溶酶原激活物(t-PA)活性、纤溶酶原激活物抑制物(PAI-1)活性、D-二聚体(D-D)、纤维蛋白原(FG)和假性血友病因子(vWF)的浓度。结果治疗组和对照组除t-PA在治疗后分别升高75.0%和67.9%外,其余4项指标在治疗后均明显降低(P<0.05或P<0.01);两组治疗后各纤溶指标比较有统计学意义(P<0.05)。结论杏丁注射液与速效救心丸联用治疗ACS能更有效地抑制ACS病人的纤溶活性。Objective To observe influence of Xingding injection with Suxiaojiuxinwan on fibrinolytic activity in patients （pts） with acute coronary syndrome（ACS）. Methods Ninety - six pts with ACS were randomly divided into treatment group （Xingding injection with Suxiaojiuxinwan） and control group （Xingding injection）. Pre - and post - therapy, concentrations of blood plasma tissue plasminogen activator （t - PA）, activator of plasminogen inhibitor （PAI- 1） activity, D - dipolymer, fibrinogen and pseudohemophil- ia factor were detected. Results four indexes were obviously decreased and t - PA rose 75.0% and 67.9% （P〈0.05 or P〈0.01）. All indexes were changed pre - and post - therapy （P〈0.05）. Conclusion Xingding injection with Suxiaojiuxinwan could effectively inhihit fibrinolytic activity of in pts with ACS.

关 键 词：杏丁注射液 速效救心丸 急性冠脉综合征 纤溶活性 

分 类 号：R259[医药卫生—中西医结合]