妇科养坤丸质量标准提高研究  

Quality standard of Fuke Yangkun Pill

作　　者：赖宇红[1] 吴垠[1] 李依信[1] 张映娜[1] 洪美华[1] 万晓玲[1] 

机构地区：[1]广东省药品检验所,广东广州510180

出　　处：《中成药》2008年第8期1167-1171,共5页Chinese Traditional Patent Medicine

基　　金：广州市科技局资助项目(2006Z3-E5181);广东省科技厅资助项目(63054)

摘　　要：目的：提高妇科养坤丸的质量标准。方法：增加了蔓荆子的显微特征，当归、川芎、香附、木香、延胡索、地黄、熟地、白芍、甘草、砂仁的TLC鉴别，黄芩苷的HPLC法含量测定。结果：成品能检出蔓荆子显微特征，能检出当归、川芎、香附、木香、延胡索、地黄、白芍、甘草、砂仁的TLC特征斑点；黄芩苷浓度在3．28～131.2μg／mL的范围内呈良好线性关系，平均回收率为100．4％，RSD1．0％（n=6），各阴性均无干扰。结论：所建立方法简便专属，重复性好，为提高妇科养坤丸质量控制提供了方法。AIM： To improve the quality standard of Fuke Yangkun Pill. METHODS： Fructus Viticis was identified by micrology, Radix Angelica sinensis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Aucklandiae, Rhizoma Corydalis , Radix Rehmanniae , Radix Rehmanniae preparata , Radix Paeoniae alba , Radix et Rhizoma Glycyrrhizae, Fructus Amomi were identified by TLC, baicalin content was determined by HPLC. RESULTS： The TLC spots were fairly clear and distinguishable, the linear range of baicalin was within 3.28-131.2 μg/mL. The average recovery was 100.4% with RSD 1.0% （n =6）. CONCLUSION： The method is simple, and specific, and can be used for quality control of Fuke Yangkun Pill.

关 键 词：妇科养坤丸 地黄 熟地黄 TLC 黄芩苷 HPLC 

分 类 号：R927.2[医药卫生—药学]