不同给药时间对非勺型高血压患者降压效果的影响  

Effect of Different Drug Administration Time on Decompression of Blood Pressure of Patients with Non-dippers Hypertension

作　　者：郑红薇[1] 王蓓[1] 张华[1] 马山珊[1] 

机构地区：[1]第二军医大学长征医院心内科,上海200003

出　　处：《解放军护理杂志》2008年第16期18-19,22,共3页Nursing Journal of Chinese People's Liberation Army

摘　　要：目的对高血压患者不同服药时间进行研究和护理干预，观察给药时间与血压昼夜节律是否相关，以探讨合理的高血压患者给药时间。方法选择高血压病住院患者共58例，随机分为两组，分别在6：00～7：00、20：00～21：00服药，监测24h动态血压。结果清晨或夜间服药均能有效降低24h平均血压。夜间给药组夜间SBP和夜间DBP显著低于清晨给药组，清晨时段SBP或DBP显著低于清晨服药组。结论通过选择恰当的给药时间，可逆转异常的昼夜血压节律，有效抑制清晨时段血压的迅速上升，降低心脑事件的发生率。Objectives To investigate the effect of nursing care interventions on the time of drug administration, to observe the correlation of drug administration time and circadian rhythm of blood pressure （BP）, so as to determine the reasonable drug administration time. Methods Fifty-eight patients with hypertension were randomly divided into two groups. Group A received drugs in the morning （6：00-7：00）. Group B received drugs in the evening （20：00-21：00）. A 24-hour ambulatory blood pressure monitoring was used in both of the two groups. Results Early morning or evening medication can effectively lower the average BP of 24 hours. The night SBP and night DBP of group B（evening treatment group） was significantly lower than those of group A （early morning delivery group）. The early morning SBP and DBP of group B were significantly lower than those of group A. Conclusion Nursing interventions could reverse the abnormal circadian rhythm of BP,inhibit the rapid rise of BP in early morning,and reduce the incidence of heart and brain accidents.

关 键 词：非勺型高血压 给药时间 降压 

分 类 号：R544.1[医药卫生—心血管疾病]