甲状旁腺摘除对肾衰大鼠免疫功能的影响  

Effect of Parathyroidectomy on the Immunity of Rats with CRF

作　　者：方文军[1] 左静南[1] 侯积寿[1] 刘秀英[1] 宋小君[1] 

机构地区：[1]上海第二医科大学附属新华医院内分泌科,200092

出　　处：《上海第二医科大学学报》1997年第6期422-423,共2页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：采用摘除甲状旁腺后的慢性肾功能衰竭（chronicrenalfailure，CRF）大鼠，以观察其对T、B细胞功能的影响。结果显示：CRF时T、B细胞功能明显低下，而摘除甲状旁腺可提高CRF鼠T细胞转化与IL－2水平以及B细胞抗体分泌滴度，提示CRF时T、B细胞功能缺陷与继发性甲旁亢有关。The effect of parathyroidectomy on the immunity was observed in rats with chronic renal failure. Results showed that parathyroidectomy could improve serum anti-HBs level, T lymphocyte proliferation and IL-2 production by T cells of CRF rats. It suggests that secondary hyperparathyroidism might be related to the immunity functional disturbance of CRF rats.

关 键 词：肾功能衰竭 免疫功能 甲状旁腺摘除 

分 类 号：R653[医药卫生—外科学] R692.5[医药卫生—临床医学]